Description

Nesfatin-1 (30-59) (Mouse, Rat) is a specific bioactive peptide fragment derived from the NUCB2/Nesfatin-1 precursor protein, with the CAS registry number 1872441-22-9. This compound is of significant interest for its role in metabolic regulation and appetite control, serving as a critical research tool in neuroendocrinology and obesity studies. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) focused on metabolic disorders and central nervous system signaling pathways.

Application

• Neuroscientific Research: Investigation of central mechanisms regulating food intake, energy homeostasis, and body weight.
• Metabolic Disorder Studies: In vitro and in vivo research targeting pathways relevant to diabetes, obesity, and metabolic syndrome.
• Receptor Binding & Signal Transduction Assays: Used to study interaction with putative receptors and downstream cellular signaling events.
• Biomarker Development: Exploration of Nesfatin-1 fragments as potential biomarkers for metabolic or stress-related conditions.
• Preclinical Model Validation: Essential for establishing and validating rodent models (mouse, rat) of appetite dysregulation.
• Peptide Structure-Activity Relationship (SAR) Studies: Serves as a reference compound for designing and testing novel peptide analogs.

Basic Information

Product Name	Nesfatin-1 (30-59) (Mouse, Rat)
CAS No.	1872441-22-9
Molecular Formula	C147H244N48O45S
Molecular Weight	3379.9 g/mol
Synonyms	Nesfatin-1 Fragment (30-59); NUCB2(30-59); Mouse/Rat Nesfatin-1 (30-59); NEFA/NUCB2-derived Peptide; Nucleobindin-2-derived Peptide; Anorexigenic Peptide Fragment; NUCB2 Peptide (30-59)
EINECS	Contact for details

Quality Control

Our Nesfatin-1 (30-59) (Mouse, Rat) is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, peptide content, and solvent residues.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This hygroscopic (moisture-sensitive) peptide should be allowed to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake. For optimal performance, prepare aliquots to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Composition	Conforms to theoretical values
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.