Description

Nesfatin-1 (30-59) (Human) is a bioactive peptide fragment derived from the NUCB2/Nesfatin-1 precursor protein. This specific sequence is critical for research into metabolic regulation, appetite control, and related neuroendocrine pathways. It is an essential tool for pharmaceutical R&D, academic research, and diagnostic assay development focused on obesity, diabetes, and stress responses.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the role of Nesfatin-1 in energy homeostasis, food intake, and glucose metabolism.
• Drug Discovery & Development: Serves as a key pharmacophore for screening and developing novel therapeutics targeting the Nesfatin-1 receptor pathway for metabolic disorders.
• In Vitro & In Vivo Studies: Applied in cell-based assays and animal models to elucidate signaling mechanisms and physiological effects of Nesfatin-1.
• Diagnostic Development: Utilized in the development and calibration of immunoassays (e.g., ELISA) for the quantitative detection of Nesfatin-1 in biological samples.
• Receptor Binding Studies: Employed in competitive binding assays to characterize receptor affinity and specificity.

Basic Information

Product Name	Nesfatin-1 (30-59) (Human)
CAS No.	1872441-21-8
Molecular Formula	C149H238N44O45S
Molecular Weight	~3350.8 g/mol
Synonyms	Nesfatin-1 (30-59); Nesfatin-1 Fragment (30-59); Human Nesfatin-1 (30-59); NUCB2(30-59); NEFA/NUCB2-derived Peptide; Nucleobindin-2-derived Peptide (30-59); Appetite-Regulating Peptide Fragment
EINECS	Contact for details

Quality Control

Every batch of Nesfatin-1 (30-59) (Human) is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and biological activity. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, HPLC profile, mass spectrometry (MS) data, and endotoxin levels is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Composition	Conforms to theoretical values
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.