Description

H-Glu-Cys-Leu-Trp-Met-Asp-Trp-Val-Thr-Glu-Lys-Asn-Ile-Asn-Gly-His-Gln-Ala-Lys-Phe-Phe-Ala-Cys-Ile-Oh, (Disulfide Bond) is a synthetic peptide featuring a critical intramolecular disulfide bridge that stabilizes its bioactive conformation. This compound is of significant interest for advanced research in biochemistry and pharmacology, particularly in the study of protein folding, receptor-ligand interactions, and signal transduction pathways. It serves as a crucial building block and reference standard for scientists and developers in the pharmaceutical, biotechnology, and life science research sectors.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the discovery and development of novel peptide-based therapeutics.
• Biochemical Research: For studying the structure-activity relationships (SAR) of peptides, the role of disulfide bonds in protein stability, and enzyme-substrate interactions.
• Cell Biology Studies: Investigation of cellular signaling pathways, receptor binding assays, and as a tool compound in functional genomics.
• Diagnostic Development: Potential use as an antigen or calibrator in the development of immunoassays and diagnostic kits.
• Cosmeceutical Research: Exploration of bioactive peptides for potential applications in advanced skincare formulations targeting specific cellular functions.

Basic Information

Product Name	H-Glu-Cys-Leu-Trp-Met-Asp-Trp-Val-Thr-Glu-Lys-Asn-Ile-Asn-Gly-His-Gln-Ala-Lys-Phe-Phe-Ala-Cys-Ile-Oh, (Disulfide Bond)
CAS No.	1872435-10-3
Molecular Formula	C133H193N33O38S3
Molecular Weight	~2984.42 g/mol
Synonyms	Cyclic Peptide 1872435-10-3; Disulfide-linked 25-mer peptide; H-ECLWM-DWVTEKNINGHQAKFFACI-OH (Disulfide bond: Cys2-Cys24); Glu-Cys-Leu-Trp-Met-Asp-Trp-Val-Thr-Glu-Lys-Asn-Ile-Asn-Gly-His-Gln-Ala-Lys-Phe-Phe-Ala-Cys-Ile cyclic (2->24)-disulfide; Synthetic bioactive peptide with intramolecular disulfide bridge
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of H-Glu-Cys-Leu-Trp-Met-Asp-Trp-Val-Thr-Glu-Lys-Asn-Ile-Asn-Gly-His-Gln-Ala-Lys-Phe-Phe-Ala-Cys-Ile-Oh, (Disulfide Bond) undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in water, DMSO, or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.