Description

Neuronostatin-13 (Mouse, Rat), H-Leu-Arg-Gln-Phe-Leu-Gln-Lys-Ser-Leu-Ala-Ala-Ala-Thr-Nh2, Trifluoroacetate is a synthetic peptide analog of the endogenous neuropeptide neuronostatin, provided as a trifluoroacetate salt for enhanced stability and solubility. This compound is a critical research tool for investigating the role of neuronostatin in metabolic regulation, cardiovascular function, and central nervous system signaling. It is essential for academic, pharmaceutical, and biotechnology researchers focused on neuroendocrinology, diabetes, obesity, and cardiovascular disease models.

Application

• Neuroscientific Research: Used as a reference standard and active agent in studies exploring neuronostatin's effects on neuronal excitability, feeding behavior, and stress responses in rodent models.
• Metabolic Disorder Studies: Applied in vitro and in vivo to investigate the peptide's role in insulin secretion, glucose homeostasis, and the pathophysiology of diabetes and obesity.
• Cardiovascular Research: Utilized to examine the effects on blood pressure, cardiac contractility, and vascular tone in preclinical models.
• Receptor Binding & Signal Transduction Assays: Serves as a high-purity ligand for characterizing putative neuronostatin receptors and downstream signaling pathways.
• Antibody Production & Validation: Acts as a critical immunogen and standard for developing and validating specific antibodies for immunohistochemistry and ELISA.
• Pharmaceutical Screening: Employed in high-throughput screening campaigns to identify modulators of the neuronostatin pathway for potential therapeutic development.

Basic Information

Product Name	Neuronostatin-13 (Mouse, Rat), H-Leu-Arg-Gln-Phe-Leu-Gln-Lys-Ser-Leu-Ala-Ala-Ala-Thr-Nh2, Trifluoroacetate
CAS No.	1872435-05-6
Molecular Formula	C71H124N24O20 • xC2HF3O2
Molecular Weight	~1630.9 g/mol (free base)
Synonyms	Neuronostatin-13 (mouse); Neuronostatin-13 (rat); NST-13; H-Leu-Arg-Gln-Phe-Leu-Gln-Lys-Ser-Leu-Ala-Ala-Ala-Thr-NH2; LRQFLQKSLAAAT-NH2; Peptide NST 13; Mouse/Rat Neuronostatin-13 TFA salt
EINECS	Contact for details

Quality Control

Our Neuronostatin-13 (Mouse, Rat) TFA is manufactured under strict quality systems suitable for research use. Each batch is subjected to rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity by HPLC, molecular weight confirmation by Mass Spectrometry, and peptide content are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting to minimize freeze-thaw cycles and maintain stability.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular ion peak consistent with theoretical mass
Purity (HPLC)	≥95%
Peptide Content	≥70% (by weight)
Amino Acid Analysis	Complies with theoretical composition
Solubility	Soluble in water, aqueous acetic acid, or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.