Description

(Des-Gly10,D-His2,D-Trp6,Pro-Nhet9)-Lhrh CAS NO 1872435-01-2 is a synthetic, modified peptide analog of Gonadotropin-Releasing Hormone (GnRH). This compound is engineered for enhanced stability and specific receptor binding affinity, making it a critical research tool and a potential candidate for therapeutic development. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on endocrinology, oncology, and reproductive medicine.

Application

• Pharmaceutical Research & Development: As a lead compound for developing novel GnRH receptor agonists or antagonists targeting hormone-dependent conditions.
• Endocrinology Studies: Investigating the hypothalamic-pituitary-gonadal axis, hormone regulation, and feedback mechanisms in preclinical models.
• Oncology Research: Exploring applications in the treatment of hormone-sensitive cancers, such as prostate and breast cancer.
• Reproductive Medicine: Studying fertility control, ovulation induction, and related disorders.
• Biochemical Assay Standard: Serving as a high-purity reference standard in bioanalytical method development and validation (HPLC, LC-MS).
• Peptide Chemistry & Drug Design: Used as a model compound for studying structure-activity relationships (SAR) and peptide modification techniques.

Basic Information

Product Name	(Des-Gly10,D-His2,D-Trp6,Pro-Nhet9)-Lhrh
CAS No.	1872435-01-2
Molecular Formula	C58H78N16O12
Molecular Weight	1151.34 g/mol
Synonyms	Des-Gly10,D-His2,D-Trp6,Pro-NHEt9-LHRH; GnRH Analog; LHRH Agonist Analog; Modified Luteinizing Hormone-Releasing Hormone; (Des-Gly10,D-His2,D-Trp6,Pro-NHEt9)-LHRH; Gonadorelin Analog; pGlu-His-Trp-Ser-Tyr-D-His-Leu-Arg-Pro-NHEt; 1872435-01-2
EINECS	Contact for details

Quality Control

Our (Des-Gly10,D-His2,D-Trp6,Pro-Nhet9)-Lhrh is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.