Description

(Des-Gly10,D-His2,D-Ser(Tbu)6,Pro-Nhet9)-Lhrh is a synthetic peptide analog of Gonadotropin-Releasing Hormone (GnRH), a key regulator of the reproductive endocrine system. This compound is engineered for enhanced stability and specific receptor binding, making it a critical intermediate in advanced pharmaceutical research and development. It is primarily utilized by biotechnology firms and pharmaceutical manufacturers focused on developing novel therapeutics in the fields of endocrinology, oncology, and reproductive medicine.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced GnRH agonist or antagonist drug candidates.
• Endocrine Research: Used in preclinical studies to investigate the hypothalamic-pituitary-gonadal axis and related disorders.
• Oncology R&D: Applied in the development of targeted therapies for hormone-dependent cancers, such as prostate and breast cancer.
• Veterinary Medicine: Potential use in developing fertility control and reproductive management solutions for animals.
• Biochemical Tool: Functions as a high-purity reference standard in analytical method development and quality control laboratories.
• Peptide Chemistry Studies: Utilized in academic and industrial research to study structure-activity relationships (SAR) of modified peptide hormones.

Basic Information

Product Name	(Des-Gly10,D-His2,D-Ser(Tbu)6,Pro-Nhet9)-Lhrh
CAS No.	1872434-99-5
Molecular Formula	C58H78N16O12
Molecular Weight	1151.3 g/mol
Synonyms	GnRH Analog; LHRH Analog; (Des-Gly10,D-His2,D-Ser(tBu)6,Pro-NHEt9)-LHRH; Gonadorelin Analog; Modified Luteinizing Hormone-Releasing Hormone; D-His2, D-Ser(tBu)6, Pro-NHEt9-LHRH (1-9) Decapeptide Amide; Synthetic GnRH Peptide Fragment; 1872434-99-5
EINECS	Contact for details

Quality Control

Our (Des-Gly10,D-His2,D-Ser(Tbu)6,Pro-Nhet9)-Lhrh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, keep desiccated under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, Acetic Acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.