Description

5-(Piperidin-4-Yl)Pyrimidine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a versatile pyrimidine-piperidine scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel drug candidates. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers targeting therapeutic areas such as oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates, particularly kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study biological pathways and target validation.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of proprietary compounds and active pharmaceutical ingredients (APIs).
• Library Synthesis: A valuable building block for creating diverse compound libraries for high-throughput screening (HTS).

Basic Information

Product Name	5-(Piperidin-4-Yl)Pyrimidine Dihydrochloride
CAS No.	1864059-34-6
Molecular Formula	C9H14Cl2N3
Molecular Weight	235.13 g/mol
Synonyms	5-(4-Piperidinyl)pyrimidine dihydrochloride; 4-(Pyrimidin-5-yl)piperidine dihydrochloride; 5-Piperidin-4-yl-pyrimidine dihydrochloride; 5-(Piperidin-4-yl)pyrimidine hydrochloride (1:2); 1864059-34-6; 5-(4-Piperidyl)pyrimidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 5-(Piperidin-4-Yl)Pyrimidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.