Description

6-Chloro-2,4-Difluoro-3-Methylbenzyl Alcohol is a high-value fluorinated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its structure, featuring chlorine and fluorine substituents on the aromatic ring, makes it an essential intermediate for creating molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the difluoro and chloro groups contribute to bioavailability and binding affinity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic display materials, enhancing stability and performance.
• Organic Ligand & Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis, facilitating challenging cross-coupling and fluorination reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring complex, multi-substituted benzyl alcohol frameworks.

Basic Information

Product Name	6-Chloro-2,4-Difluoro-3-Methylbenzyl Alcohol
CAS No.	1858240-87-5
Molecular Formula	C8H7ClF2O
Molecular Weight	192.59 g/mol
Synonyms	(6-Chloro-2,4-difluoro-3-methylphenyl)methanol; 2,4-Difluoro-6-chloro-3-methylbenzyl Alcohol; 3-Methyl-2,4,6-trifluorobenzyl Alcohol (partial structure analog); Benzyl alcohol, 6-chloro-2,4-difluoro-3-methyl-; FC-6873 (Potential internal code); PharmaBlock PB-DFCMBA (Potential catalog code); 1858240-87-5; DFCMBA
EINECS	Contact for details

Quality Control

Our 6-Chloro-2,4-Difluoro-3-Methylbenzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.