Description

Ethyl 2,4-Dichloroquinazoline-6-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinazoline-based drug candidates, including potential kinase inhibitors, anticancer agents, and antimicrobial compounds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactive quinazoline core.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, ligands for catalysis, or specialty polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploring new chemical reactions in heterocyclic chemistry.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) engaged in custom synthesis projects from gram to kilogram scale.

Basic Information

Product Name	Ethyl 2,4-Dichloroquinazoline-6-Carboxylate
CAS No.	1841081-27-3
Molecular Formula	C11H8Cl2N2O2
Molecular Weight	271.10 g/mol
Synonyms	Ethyl 2,4-dichloro-6-quinazolinecarboxylate; 2,4-Dichloroquinazoline-6-carboxylic Acid Ethyl Ester; 6-Carbethoxy-2,4-dichloroquinazoline; 2,4-Dichloro-6-(ethoxycarbonyl)quinazoline; Quinazoline-6-carboxylic acid, 2,4-dichloro-, ethyl ester; Ethyl 2,4-dichloro-6-quinazolinecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2,4-Dichloroquinazoline-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.