Description

(R)-1-(3-(4-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-1-Yl)Piperidin-1-Yl)Propan-1-One is a high-purity, chiral small molecule building block of significant interest in advanced pharmaceutical research and development. Its complex heterocyclic structure, featuring a pyrazolopyrimidine core, makes it a valuable intermediate for the synthesis of targeted therapeutic agents. This compound is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel kinase inhibitors and other targeted small molecule drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Biochemical Tool Compound: Potential use in developing assay probes for studying specific enzymatic pathways in biological systems.
• Custom Synthesis: Starting material for the contract manufacturing of specialized, non-commercial research compounds.

Basic Information

Product Name	(R)-1-(3-(4-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-1-Yl)Piperidin-1-Yl)Propan-1-One
CAS No.	1839099-22-7
Molecular Formula	C25H26N6O2
Molecular Weight	442.52 g/mol
Synonyms	(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one; UNII-9QZ80IEA8S; 9QZ80IEA8S; (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]propan-1-one; (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one; ACP-319; ACP 319; ACP319
EINECS	Contact for details

Quality Control

Our (R)-1-(3-(4-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-1-Yl)Piperidin-1-Yl)Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research-grade and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.