Description

2-Fluoro-4-Methyl-3-(Trifluoromethyl)Benzylamine is a high-purity, multi-fluorinated benzylamine derivative, a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart desirable properties such as enhanced metabolic stability, lipophilicity, and bioavailability in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in oncology, CNS, and antiviral research where fluorinated compounds are prevalent.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atoms to improve compound activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a labeling reagent or a building block for chemical probes due to its amine functionality, which can be readily conjugated.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) for constructing complex aromatic amines.

Basic Information

Product Name	2-Fluoro-4-Methyl-3-(Trifluoromethyl)Benzylamine
CAS No.	1824271-19-3
Molecular Formula	C9H7F4N
Molecular Weight	205.15 g/mol
Synonyms	2-Fluoro-4-methyl-3-(trifluoromethyl)benzenemethanamine; (2-Fluoro-4-methyl-3-(trifluoromethyl)phenyl)methanamine; 1-(Aminomethyl)-2-fluoro-4-methyl-3-(trifluoromethyl)benzene; 2-Fluoro-α-methyl-3-(trifluoromethyl)benzylamine; 3-(Trifluoromethyl)-2-fluoro-4-methylbenzylamine; Benzenemethanamine, 2-fluoro-4-methyl-3-(trifluoromethyl)-; 1824271-19-3
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Methyl-3-(Trifluoromethyl)Benzylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.