Description

3-Bromo-4-Chloro-2-Fluorobenzyl Alcohol is a high-purity, multi-halogenated benzyl alcohol derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its precise halogen substitution pattern makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors, where it is instrumental in the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the halogen atoms for bioactivity and metabolic stability.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Intermediate for synthesizing functionalized monomers and polymers with unique optical or electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthesis projects requiring high-fidelity halogenated intermediates.
• Academic Research: Used in university and institutional labs for methodological development and exploring new chemical reactions.

Basic Information

Product Name	3-Bromo-4-Chloro-2-Fluorobenzyl Alcohol
CAS No.	1824057-69-3
Molecular Formula	C7H5BrClFO
Molecular Weight	239.47 g/mol
Synonyms	(3-Bromo-4-chloro-2-fluorophenyl)methanol; 2-Fluoro-3-bromo-4-chlorobenzyl alcohol; 1-(Bromomethyl)-2-chloro-5-fluoro-4-bromobenzene (incorrect but common search variant); Benzyl alcohol, 3-bromo-4-chloro-2-fluoro-; α-Hydroxymethyl-3-bromo-4-chloro-2-fluorobenzene
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-Chloro-2-Fluorobenzyl Alcohol is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.