Description

5-Bromo-4-(2-Fluoropropan-2-Yl)Pyrimidine is a high-value, halogenated pyrimidine derivative serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both bromine and fluorine substituents, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine moiety enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological mechanisms.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form new carbon-carbon bonds.
• Library Synthesis for High-Throughput Screening: Used in combinatorial chemistry to generate diverse compound libraries for biological screening.

Basic Information

Product Name	5-Bromo-4-(2-Fluoropropan-2-Yl)Pyrimidine
CAS No.	1823944-93-9
Molecular Formula	C7H7BrFN3
Molecular Weight	232.05 g/mol
Synonyms	4-(2-Fluoro-2-propanyl)-5-bromopyrimidine; 5-Bromo-4-(2-fluoropropan-2-yl)pyrimidine; 5-Bromo-4-(2-fluoroisopropyl)pyrimidine; 5-Bromo-4-(1-fluoro-1-methylethyl)pyrimidine; Pyrimidine, 5-bromo-4-(2-fluoropropan-2-yl)-; 1823944-93-9
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-4-(2-Fluoropropan-2-Yl)Pyrimidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.