Description

5-Bromo-4-Chloro-6-(2-Fluoropropan-2-Yl)Pyrimidine is a high-value, multi-halogenated pyrimidine building block essential for advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogen pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific steric and electronic properties into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for constructing complex nitrogen-containing ligands used in catalytic systems.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific halogenated pyrimidine cores.
• Academic & Industrial R&D: Used in exploratory chemistry to study structure-activity relationships (SAR) and novel reaction pathways.

Basic Information

Product Name	5-Bromo-4-Chloro-6-(2-Fluoropropan-2-Yl)Pyrimidine
CAS No.	1823900-57-7
Molecular Formula	C7H6BrClFN2
Molecular Weight	267.49 g/mol
Synonyms	6-(2-Fluoro-2-propanyl)-5-bromo-4-chloropyrimidine; 5-Bromo-4-chloro-6-(2-fluoropropan-2-yl)pyrimidine; 4-Chloro-5-bromo-6-(2-fluoroisopropyl)pyrimidine; 5-Bromo-4-chloro-6-(1-fluoro-1-methylethyl)pyrimidine; 2-Fluoro-2-(5-bromo-4-chloropyrimidin-6-yl)propane; Pyrimidine, 5-bromo-4-chloro-6-(2-fluoropropan-2-yl)-; 1823900-57-7
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloro-6-(2-Fluoropropan-2-Yl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.