Description

2-Chloro-4-Ethoxy-3-Fluorophenol is a high-purity fluorinated phenolic compound, serving as a critical advanced intermediate in modern organic synthesis. Its unique halogenated and alkoxylated structure makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates requiring fluorinated phenolic motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the chloro-ethoxy-fluoro substitution pattern can enhance biological activity and selectivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized fluorinated aromatic compounds used in electronic display technologies.
• Polymer Modification Agent: Employed to introduce functional phenolic groups into polymer chains, altering properties like thermal stability, adhesion, or chemical resistance.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create complex, multi-substituted benzene derivatives for various R&D applications.

Basic Information

Product Name	2-Chloro-4-Ethoxy-3-Fluorophenol
CAS No.	1823779-02-7
Molecular Formula	C8H8ClFO2
Molecular Weight	190.60 g/mol
Synonyms	3-Fluoro-2-chloro-4-ethoxyphenol; 4-Ethoxy-3-fluoro-2-chlorophenol; 2-Chloro-4-ethoxy-3-fluorophenol; Phenol, 2-chloro-4-ethoxy-3-fluoro-; 1823779-02-7
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Ethoxy-3-Fluorophenol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Custom purity grades, including research and GMP standards, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.