Description

3-Chloro-4-ethoxy-2-fluorobenzaldehyde is a high-purity, multi-functional aromatic aldehyde building block of significant interest in advanced organic synthesis. Its unique substitution pattern, featuring chloro, ethoxy, and fluoro groups, makes it a versatile and valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom often enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Development: Serves as a building block for creating novel organic semiconductors, charge-transport materials, and liquid crystal compounds for display technologies.
• Organic Synthesis & Chemical Research: Employed in academic and industrial R&D for palladium-catalyzed cross-coupling reactions, nucleophilic aromatic substitution, and as a scaffold for library synthesis in drug discovery.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the aldehyde group facilitates condensation reactions to form chromophores.

Basic Information

Product Name	3-Chloro-4-ethoxy-2-fluorobenzaldehyde
CAS No.	1823430-49-4
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	2-Fluoro-3-chloro-4-ethoxybenzaldehyde; 4-Ethoxy-2-fluoro-3-chlorobenzaldehyde; 3-Chloro-4-ethoxy-2-fluorobenzenecarboxaldehyde; Benzaldehyde, 3-chloro-4-ethoxy-2-fluoro-; CAS 1823430-49-4
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-ethoxy-2-fluorobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We can supply material compliant with various pharmaceutical intermediate standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.