Description

4-(Aminomethyl)-5-Bromo-2-(Methylthio)Pyrimidine is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile building block for constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides due to its bioactive pyrimidine core.
• Chemical Biology & Proteomics: Acts as a valuable scaffold or linker for creating molecular probes and bioconjugates.
• Material Science Research: Employed in the synthesis of organic electronic materials and ligands for catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale API batches.
• Academic Research: Used in university and institutional labs for methodological studies and novel reaction development.

Basic Information

Product Name	4-(Aminomethyl)-5-Bromo-2-(Methylthio)Pyrimidine
CAS No.	1823402-38-5
Molecular Formula	C6H8BrN3S
Molecular Weight	234.12 g/mol
Synonyms	5-Bromo-2-(methylthio)-4-pyrimidinemethanamine; 4-(Aminomethyl)-5-bromo-2-methylsulfanylpyrimidine; 5-Bromo-2-(methylthio)-4-(aminomethyl)pyrimidine; 2-(Methylthio)-5-bromo-4-pyrimidinemethanamine; 4-Pyrimidinemethanamine, 5-bromo-2-(methylthio)-; 1823402-38-5
EINECS	Contact for details

Quality Control

Every batch of 4-(Aminomethyl)-5-Bromo-2-(Methylthio)Pyrimidine is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to support regulatory filings in pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.