Description

Quinazoline, 2-Bromo-5-Chloro- is a halogenated quinazoline derivative, a high-value chemical intermediate prized for its role in constructing complex molecular architectures. This compound is critical for research and development in advanced pharmaceutical synthesis, particularly in the creation of novel active pharmaceutical ingredients (APIs). It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactive quinazoline core.
• Material Science: Acts as a precursor for the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology: Employed as a molecular probe or scaffold in biochemical assays and for studying protein-ligand interactions.
• Academic & Contract Research: Essential for organic synthesis research in universities and contract research organizations (CROs) exploring new heterocyclic chemistry.

Basic Information

Product Name	Quinazoline, 2-Bromo-5-Chloro-
CAS No.	1823381-69-6
Molecular Formula	C8H4BrClN2
Molecular Weight	243.49 g/mol
Synonyms	2-Bromo-5-chloroquinazoline; 5-Chloro-2-bromoquinazoline; Quinazoline, 5-chloro-2-bromo-; 2-Bromo-5-chloro-quinazoline; 1823381-69-6
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Chloroquinazoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.