Description

3-Fluoro-4-Iodo-2-Nitro-Phenylamine is a high-purity, multi-functional halogenated aniline derivative, distinguished by its unique substitution pattern. This compound is a critical pharmaceutical intermediate and organic synthesis building block, valued for its ability to introduce both fluorine and iodine atoms into complex molecular frameworks. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Organic Synthesis Building Block: Serves as a versatile reagent for cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution, enabling complex molecule construction.
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology Probe Development: Useful for creating tagged molecules or affinity probes for studying biological pathways and protein interactions.

Basic Information

Product Name	3-Fluoro-4-Iodo-2-Nitro-Phenylamine
CAS No.	1823370-15-5
Molecular Formula	C6H4FIN2O2
Molecular Weight	282.01 g/mol
Synonyms	2-Nitro-3-fluoro-4-iodoaniline; 4-Iodo-3-fluoro-2-nitroaniline; 3-Fluoro-4-iodo-2-nitrobenzenamine; Benzenamine, 3-fluoro-4-iodo-2-nitro-; 3-Fluoro-4-iodo-2-nitro-phenylamine; 1823370-15-5
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-Iodo-2-Nitro-Phenylamine is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.