Description

2-Fluoro-4-Methyl-3-(Trifluoromethyl)Phenol is a high-value fluorinated phenolic intermediate with a unique trifluoromethyl substitution pattern. This compound is critical for introducing fluorine atoms into target molecules, significantly altering their physicochemical properties such as metabolic stability, lipophilicity, and bioavailability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, contributing to the molecular design of fluorinated liquid crystals and organic light-emitting diode (OLED) components.
• Polymer Modification: Employed to introduce fluorinated phenolic groups into polymer chains, improving material properties like chemical resistance, thermal stability, and surface characteristics.
• Chemical Research & Development: A versatile reagent for organic synthesis, enabling the exploration of new fluorination methodologies and the creation of complex molecular architectures in academic and industrial labs.

Basic Information

Product Name	2-Fluoro-4-Methyl-3-(Trifluoromethyl)Phenol
CAS No.	1823323-63-2
Molecular Formula	C8H6F4O
Molecular Weight	194.13 g/mol
Synonyms	2-Fluoro-4-methyl-3-(trifluoromethyl)phenol; 3-(Trifluoromethyl)-2-fluoro-4-methylphenol; 2-Fluoro-α,α,α,4-tetramethylphenol; Phenol, 2-fluoro-4-methyl-3-(trifluoromethyl)-; 4-Methyl-2-fluoro-3-trifluoromethylphenol
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Methyl-3-(Trifluoromethyl)Phenol is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.