Description

3-Bromo-5-Fluoro-2-Methoxyaniline Hydrochloride is a high-purity, halogenated aniline derivative salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic core with multiple reactive handles—bromo, fluoro, and methoxy groups—enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Dye and Pigment Intermediate: Employed in the production of complex, high-performance dyes and pigments due to its aniline backbone and substituents.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for diagnostic and research applications.

Basic Information

Product Name	3-Bromo-5-Fluoro-2-Methoxyaniline Hydrochloride
CAS No.	1820747-56-5
Molecular Formula	C7H8BrClFNO
Molecular Weight	256.50 g/mol
Synonyms	2-Methoxy-3-bromo-5-fluoroaniline hydrochloride; 3-Bromo-5-fluoro-2-methoxybenzenamine hydrochloride; 5-Fluoro-3-bromo-2-methoxyaniline HCl; 2-Amino-6-bromo-4-fluoroanisole hydrochloride; Benzenamine, 3-bromo-5-fluoro-2-methoxy-, hydrochloride; 3-Bromo-5-fluoro-o-anisidine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoro-2-Methoxyaniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.