Description

2-(Bromomethyl)-5-Fluorobenzenesulphonylchloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its unique structure, featuring both a reactive sulfonyl chloride and a bromomethyl group, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including protease inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging the fluorinated aromatic system for enhanced bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Utilized to create activity-based probes (ABPs) for studying enzyme function and mechanism.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses producing bespoke compounds for client R&D projects.

Basic Information

Product Name	2-(Bromomethyl)-5-Fluorobenzenesulphonylchloride
CAS No.	1820717-41-6
Molecular Formula	C7H5BrClFO2S
Molecular Weight	287.53 g/mol
Synonyms	5-Fluoro-2-(bromomethyl)benzenesulfonyl chloride; 2-Bromomethyl-5-fluorobenzenesulfonyl chloride; 1-Bromomethyl-4-fluoro-2-sulfonylchloridebenzene; Benzenesulfonyl chloride, 2-(bromomethyl)-5-fluoro-; α-Bromo-4-fluoro-o-toluenesulfonyl chloride; 4-Fluoro-α-bromo-o-toluenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 2-(Bromomethyl)-5-Fluorobenzenesulphonylchloride adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.