Description

3-Bromo-6-Chloro-2-Fluoroaniline, n-Boc protected, Tech is a high-purity, protected aniline derivative serving as a critical building block in advanced organic synthesis. This compound is essential for the efficient and selective construction of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially those containing halogenated aniline motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the specific halogen pattern is crucial for bioactivity.
• Material Science Research: Serves as a precursor for functionalized monomers or ligands in the creation of specialty polymers and advanced materials.
• Cross-Coupling Reactions: The bromo and chloro substituents make it a valuable substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Protecting Group Chemistry: The n-Boc (tert-butoxycarbonyl) group allows for selective deprotection, enabling sophisticated multi-step synthetic routes.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds or molecular probes for biochemical and pharmacological studies.

Basic Information

Product Name	3-Bromo-6-Chloro-2-Fluoroaniline, n-Boc protected, Tech
CAS No.	1820711-67-8
Molecular Formula	C11H12BrClFNO2
Molecular Weight	324.58 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-bromo-6-chloro-2-fluoroaniline; tert-Butyl (3-bromo-6-chloro-2-fluorophenyl)carbamate; N-Boc-3-bromo-6-chloro-2-fluoroaniline; 3-Bromo-6-chloro-2-fluoro-N-[(2-methylpropan-2-yl)oxycarbonyl]aniline; Boc-3-Br-6-Cl-2-F-aniline; Carbamic acid, N-(3-bromo-6-chloro-2-fluorophenyl)-, 1,1-dimethylethyl ester; 3-Bromo-6-chloro-2-fluoroaniline Boc derivative
EINECS	Contact for details

Quality Control

Our technical grade 3-Bromo-6-Chloro-2-Fluoroaniline, n-Boc protected is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets the requirements for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.