Description

N2-(4-Fluorophenyl)Pyridine-2,3-Diamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1820711-57-6. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated heterocyclic structures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecules containing pyridine and aniline moieties.
• Research & Development (R&D): Essential for academic and industrial research in pharmacology and organic chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Research: Potential application in the development of new fluorinated agrochemicals and pesticides.
• Material Science: Can serve as a monomer or ligand in the development of specialized polymers or metal-organic frameworks (MOFs).

Basic Information

Product Name	N2-(4-Fluorophenyl)Pyridine-2,3-Diamine Dihydrochloride
CAS No.	1820711-57-6
Molecular Formula	C11H11FN3·2HCl
Molecular Weight	277.14 g/mol (Free base: 201.23 g/mol)
Synonyms	2,3-Diamino-N-(4-fluorophenyl)pyridinium dichloride; 4-Fluoro-N-(2,3-diaminopyridin-4-yl)aniline dihydrochloride; N-(4-Fluorophenyl)-2,3-pyridinediamine dihydrochloride; 2,3-Pyridinediamine, N-(4-fluorophenyl)-, dihydrochloride; 1820711-57-6; N2-(4-Fluorophenyl)-2,3-diaminopyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our N2-(4-Fluorophenyl)Pyridine-2,3-Diamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.