Description

1,3-Diethyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazoline-6-Sulfonyl Chloride is a high-value, reactive sulfonyl chloride derivative of a functionalized quinazoline core. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for the synthesis of complex molecules. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Acts as a reactive handle for labeling proteins or other biomolecules due to its sulfonyl chloride group.
• Material Science Research: Intermediate for creating functional polymers or organic electronic materials with the quinazoline moiety.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke chemical synthesis projects.

Basic Information

Item	Details
Product Name	1,3-Diethyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazoline-6-Sulfonyl Chloride
CAS No.	1820707-02-5
Molecular Formula	C₁₂H₁₃ClN₂O₄S
Molecular Weight	316.76 g/mol
Synonyms	6-(Chlorosulfonyl)-1,3-diethyl-1,2,3,4-tetrahydro-2,4-dioxoquinazoline; 1,3-Diethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonyl chloride; Quinazoline-6-sulfonyl chloride, 1,3-diethyl-1,2,3,4-tetrahydro-2,4-dioxo-; 1,3-Diethyl-2,4-dioxotetrahydroquinazoline-6-sulfonyl chloride; DEQDSC
EINECS	Contact for details

Quality Control

Our 1,3-Diethyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazoline-6-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR, and IR for structural confirmation, to ensure it meets exacting standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.