Description

Diethyl 5-Bromopyrimidine-4,6-Dicarboxylate is a high-purity brominated pyrimidine derivative, a crucial advanced intermediate in modern organic synthesis. This compound matters for its role as a versatile building block, enabling the construction of complex heterocyclic scaffolds with precision. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the pyrimidine core's bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials and metal-organic frameworks (MOFs) due to its functionalized aromatic structure.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for biochemical assays and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	Diethyl 5-Bromopyrimidine-4,6-Dicarboxylate
CAS No.	1820687-49-7
Molecular Formula	C10H11BrN2O4
Molecular Weight	303.11 g/mol
Synonyms	5-Bromopyrimidine-4,6-dicarboxylic acid diethyl ester; Diethyl 5-bromo-4,6-pyrimidinedicarboxylate; 4,6-Pyrimidinedicarboxylic acid, 5-bromo-, diethyl ester; 5-Bromo-4,6-di(ethoxycarbonyl)pyrimidine; 5-Bromo-4,6-bis(ethoxycarbonyl)pyrimidine; 5-Bromopyrimidine-4,6-dicarboxylate diethyl ester; 1820687-49-7
EINECS	Contact for details

Quality Control

Our Diethyl 5-Bromopyrimidine-4,6-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.