Description

2-(4-Oxopyrido[2,3-D]Pyrimidin-3(4H)-Yl)Acetic Acid Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant interest in modern medicinal chemistry. This compound matters for its role as a key precursor in the synthesis of complex heterocyclic molecules, enabling the development of novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and development of new drugs, particularly those targeting kinase inhibition and other critical biological pathways.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Kinase Inhibitor Research: Serves as a core scaffold in the development of small-molecule kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Chemical Synthesis: Employed in organic synthesis to construct complex pyrido[2,3-d]pyrimidine-based heterocyclic systems.
• Biochemical Research: Utilized as a tool compound for probing biological mechanisms and enzyme functions in vitro.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	2-(4-Oxopyrido[2,3-D]Pyrimidin-3(4H)-Yl)Acetic Acid Hydrochloride
CAS No.	1820666-53-2
Molecular Formula	C11H10N3O3·HCl
Molecular Weight	269.67 g/mol (Free base: 232.22 g/mol)
Synonyms	3-(Carboxymethyl)-4H-pyrido[2,3-d]pyrimidin-4-one hydrochloride; 2-[(4-Oxo-4H-pyrido[2,3-d]pyrimidin-3-yl)]acetic acid hydrochloride; 2-(4-Oxo-3,4-dihydropyrido[2,3-d]pyrimidin-3-yl)acetic acid hydrochloride; 3-(Carboxymethyl)pyrido[2,3-d]pyrimidin-4(3H)-one hydrochloride; 1820666-53-2; Pyrido[2,3-d]pyrimidine-3-acetic acid, 4-oxo-, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(4-Oxopyrido[2,3-D]Pyrimidin-3(4H)-Yl)Acetic Acid Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for each batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.