Description

Biotinyl-Pth-Related Protein (1-34) (Human, Mouse, Rat) CAS NO 1816258-59-9 is a synthetic peptide fragment designed for advanced biochemical and pharmacological research. This biotinylated analog is critical for studying parathyroid hormone-related protein (PTHrP) signaling pathways, receptor binding, and biological activity across multiple species. It is an essential reagent for researchers in academic institutions, pharmaceutical R&D, and biotechnology companies focused on bone metabolism, cancer biology, and endocrine disorders.

Application

• Biochemical Research: Used as a high-affinity ligand in receptor binding assays and affinity purification studies for PTH/PTHrP receptors.
• Signal Transduction Studies: Investigates the activation mechanisms of downstream signaling cascades, including cAMP and calcium pathways.
• Immunoassay Development: Serves as a standardized antigen or biotinylated tracer in the development of ELISA and other immunoassays.
• Cell-Based Assays: Applied in vitro to study the effects on osteoblast differentiation, proliferation, and other cellular functions.
• Proteomics & Protein Interaction Mapping: Utilized in pull-down experiments and mass spectrometry to identify novel interacting proteins.
• Drug Discovery Screening: Acts as a key component in high-throughput screening platforms for identifying PTHrP pathway modulators.

Basic Information

Product Name	Biotinyl-Pth-Related Protein (1-34) (Human, Mouse, Rat)
CAS No.	1816258-59-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Biotin-PTHrP(1-34); Biotinylated Parathyroid Hormone-Related Protein (1-34); Biotin-PTHrP; PTHrP (1-34), Biotin conjugate; Biotinyl-PTHrP (1-34) amide, human/mouse/rat; Biotin-labeled PTHrP fragment; PTHrP 1-34 Biotin
EINECS	Contact for details

Quality Control

Our Biotinyl-Pth-Related Protein (1-34) is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes rigorous analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. We provide comprehensive Certificates of Analysis (COA) detailing purity, peptide content, and biotin incorporation ratio upon request, supporting research requiring reliable and traceable reagents.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. Aliquot into single-use vials to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Biotin Incorporation	≥ 1.0 mol Biotin / mol peptide
Solubility	Soluble in water or aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.