Description

Biotinyl-Pancreatic Polypeptide (Human) is a biotin-conjugated derivative of the human pancreatic polypeptide hormone, designed for advanced biochemical research and diagnostic applications. This modified peptide is crucial for studies involving protein-protein interactions, receptor binding assays, and signal transduction pathways due to the high-affinity biotin-streptavidin system. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers focused on endocrinology, metabolic disorders, and neuroscience. The compound enables precise detection and isolation in complex biological matrices, supporting the development of sensitive analytical methods.

Application

• Biochemical Research Reagent: Used as a high-specificity probe in studying the structure, function, and signaling mechanisms of pancreatic polypeptide receptors.
• Diagnostic Assay Development: Serves as a critical component in the development of ELISA, Western blot, and other immunoassays for metabolic and endocrine research.
• Affinity Purification & Pull-Down Assays: Facilitates the isolation and purification of target proteins or receptor complexes using streptavidin-coated beads or columns.
• Cell Biology & Imaging Studies: Employed in fluorescence-activated cell sorting (FACS) and microscopy for receptor localization and trafficking studies.
• Drug Discovery & Screening: Acts as a tool compound in high-throughput screening (HTS) platforms to identify novel modulators of the NPY receptor family.
• Peptide & Antibody Conjugation Standard: Provides a reference standard for optimizing biotinylation protocols and validating conjugation efficiency.

Basic Information

Product Name	Biotinyl-Pancreatic Polypeptide (Human)
CAS No.	1816258-36-2
Molecular Formula	C210H340N64O58S2 (Representative)
Molecular Weight	~4750 g/mol (Theoretical average)
Synonyms	Biotin-PP (Human); Biotinylated Pancreatic Polypeptide, Human; Biotin-Human Pancreatic Polypeptide; PP (1-36), Human, Biotinylated; Biotinyl-PPY; Biotin-conjugated hPP; Biotin-Pancreatic Polypeptide Fragment; NPY Family Receptor Ligand, Biotinylated
EINECS	Contact for details

Quality Control

Our Biotinyl-Pancreatic Polypeptide (Human) is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dilute acetic acid, or DMSO
Biological Activity	Tested in receptor binding assay (Data on COA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.