Description

Biotinyl-Angiotensin I CAS NO 1815618-04-2 is a biotin-conjugated derivative of the decapeptide hormone Angiotensin I, designed for high-affinity capture and detection applications. This modification is critical for researchers requiring sensitive and specific analytical methods in proteomics and biochemical studies. It is an essential reagent for pharmaceutical R&D, diagnostic assay development, and advanced life science research targeting the renin-angiotensin system.

Application

• Biomarker Research & Assay Development: Used as a labeled antigen or standard in immunoassays (e.g., ELISA) for the detection and quantification of Angiotensin I and related peptides.
• Proteomics & Protein Interaction Studies: Serves as a bait molecule for affinity purification (e.g., streptavidin/avidin pull-down) to isolate and study binding partners, antibodies, or receptors.
• Diagnostic Kit Manufacturing: A key component in the production of clinical diagnostic kits for hypertension, renal function, and cardiovascular disease monitoring.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize potential drug candidates that modulate the renin-angiotensin pathway.
• Academic & Institutional Research: Facilitates fundamental research into peptide hormone signaling, metabolism, and enzyme kinetics (e.g., ACE activity).
• Quality Control & Standardization: Acts as a certified reference material (CRM) for calibrating analytical instruments and validating methods in QC laboratories.

Basic Information

Product Name	Biotinyl-Angiotensin I
CAS No.	1815618-04-2
Molecular Formula	C82H121N23O18S
Molecular Weight	1741.0 g/mol (approx.)
Synonyms	Biotin-Angiotensin I; Biotinylated Angiotensin I; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Biotin; Biotin-Ang I; Biotinyl-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu; N-Biotinyl-Angiotensin I; Biotin-conjugated Angiotensin I; Angiotensin I Biotin Labeled
EINECS	Contact for details

Quality Control

Our Biotinyl-Angiotensin I is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the stringent requirements for research and diagnostic applications. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO, or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.