Description

6,7-Dihydro-n-Methyl-n-[(3R,4R)-4-Methyl-3-Piperidinyl]-5H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of targeted therapeutics. It is primarily required by pharmaceutical companies and contract research organizations (CROs) engaged in the development of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical development.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs for new drug candidates.
• Protease Inhibitor Development: Serves as a core scaffold or precursor in the development of inhibitors targeting specific enzymatic pathways.
• Kinase Inhibitor Synthesis: Employed in the construction of novel kinase inhibitor libraries for oncology and anti-inflammatory research.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	6,7-Dihydro-n-Methyl-n-[(3R,4R)-4-Methyl-3-Piperidinyl]-5H-Pyrrolo[2,3-D]Pyrimidin-4-Amine
CAS No.	1812890-23-5
Molecular Formula	C13H21N5
Molecular Weight	247.34 g/mol
Synonyms	(3R,4R)-4-Methyl-3-[(6,7-dihydro-4-methylamino-5H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]piperidine; 5H-Pyrrolo[2,3-d]pyrimidin-4-amine, 6,7-dihydro-N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-; UNII-9J8C9V309U; 9J8C9V309U; (3R,4R)-4-Methyl-3-({4-[(methylamino)methyl]-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-yl}methyl)piperidine; (R,R)-6,7-Dihydro-N-methyl-N-(4-methylpiperidin-3-yl)-5H-pyrrolo[2,3-d]pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 6,7-Dihydro-n-Methyl-n-[(3R,4R)-4-Methyl-3-Piperidinyl]-5H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, chiral HPLC) are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.