Description

6-(1H-Indol-4-Yl)-8-Methoxy-1-Methyl-4H-[1,2,4]Triazolo[4,3-A][1,4]Benzodiazepine-4-Acetic Acid Methyl Ester is a high-purity, complex heterocyclic compound designed for advanced research and development. This molecule is of significant interest as a key synthetic intermediate or a potential active pharmaceutical ingredient (API) precursor in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on developing novel therapeutic agents, particularly within the central nervous system (CNS) and oncology fields.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel benzodiazepine and triazole-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new pharmacophores for targeted therapies.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Biochemical Screening: Employed in high-throughput screening (HTS) assays to identify potential hits for various biological targets.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and drug discovery methodologies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Item	Detail
Product Name	6-(1H-Indol-4-Yl)-8-Methoxy-1-Methyl-4H-[1,2,4]Triazolo[4,3-A][1,4]Benzodiazepine-4-Acetic Acid Methyl Ester
CAS No.	1809296-92-1
Molecular Formula	C23H21N5O3
Molecular Weight	415.45 g/mol
Synonyms	Methyl 6-(1H-indol-4-yl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetate; 6-(1H-Indol-4-yl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetic acid methyl ester; [1,2,4]Triazolo[4,3-a][1,4]benzodiazepine-4-acetic acid, 6-(1H-indol-4-yl)-8-methoxy-1-methyl-, methyl ester
EINECS	Contact for details

Quality Control

Our 6-(1H-Indol-4-Yl)-8-Methoxy-1-Methyl-4H-[1,2,4]Triazolo[4,3-A][1,4]Benzodiazepine-4-Acetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.