Description

3,4-Difluoro-2-(Trimethylsilyl)Benzaldehyde is a high-value organosilicon building block featuring both aldehyde and silyl-protecting group functionalities. This compound matters for its role as a versatile synthetic intermediate, enabling the precise construction of complex molecules in advanced chemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the stability imparted by the trimethylsilyl group.
• Material Science Research: Serves as a precursor for advanced organic electronic materials and liquid crystals, where fluorine substitution tunes electronic properties.
• Cross-Coupling Reactions: The aldehyde group and aromatic fluorines make it a suitable substrate for various palladium-catalyzed coupling reactions (e.g., Suzuki, Heck).
• Organic Synthesis Reagent: Employed in multi-step syntheses to introduce the difluorobenzaldehyde moiety under protected conditions.
• Chemical Research & Development: A valuable tool for academic and industrial chemists exploring new reaction methodologies and complex molecule construction.

Basic Information

Product Name	3,4-Difluoro-2-(Trimethylsilyl)Benzaldehyde
CAS No.	1809161-51-0
Molecular Formula	C10H12F2OSi
Molecular Weight	214.29 g/mol
Synonyms	2-(Trimethylsilyl)-3,4-difluorobenzaldehyde; 3,4-Difluoro-2-(trimethylsilyl)benzaldehyde; Benzaldehyde, 3,4-difluoro-2-(trimethylsilyl)-; 3,4-Difluoro-2-trimethylsilylbenzaldehyde; TMS-Protected 3,4-Difluorobenzaldehyde; 2-TMS-3,4-Difluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-2-(Trimethylsilyl)Benzaldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle under an inert atmosphere (e.g., nitrogen or argon) and minimize exposure to air and moisture during use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.