Description

(S)-2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)(Methyl)Amino)Non-8-Enoic Acid is a specialized, high-purity Fmoc-protected amino acid derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise stereochemistry and functional group compatibility in solid-phase peptide synthesis (SPPS). It serves as a key building block for the pharmaceutical and biotechnology industries, enabling the development of novel peptide-based therapeutics, diagnostics, and research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial Fmoc-protected amino acid building block for the automated synthesis of complex peptides.
• Pharmaceutical Research & Development: Used in the discovery and production of peptide drugs, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation & Chemical Biology: The terminal alkene (non-8-enoic acid) moiety provides a handle for site-specific modifications via click chemistry (e.g., thiol-ene) for labeling or linker attachment.
• Peptidomimetic Design: Facilitates the creation of non-natural amino acid sequences to enhance metabolic stability and binding affinity of peptide leads.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Academic & Institutional Research: Supports fundamental studies in biochemistry, medicinal chemistry, and molecular biology involving custom peptide synthesis.

Basic Information

Product Name	(S)-2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)(Methyl)Amino)Non-8-Enoic Acid
CAS No.	1808268-51-0
Molecular Formula	C26H29NO4
Molecular Weight	419.51 g/mol
Synonyms	Fmoc-N-Me-8-Nonenoic-OH; Fmoc-N-Methyl-8-nonenoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-8-nonenoic acid; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)non-8-enoic acid; Fmoc-N-methyl-8-nonenoic acid; N-Fmoc-N-methyl-8-nonenoic acid; Fmoc-N-Me-8-nonenoic acid; N-[(9-Fluorenylmethoxy)carbonyl]-N-methyl-8-nonenoic acid
EINECS	Contact for details

Quality Control

Our (S)-2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)(Methyl)Amino)Non-8-Enoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive spectroscopic identification (NMR, MS). Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research and cGMP-grade requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dry, freezer environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.