Description

Fmoc-L-2-Methylamino-7-Octenoic Acid CAS NO 1808268-11-2 is a high-purity, non-proteinogenic amino acid derivative featuring an Fmoc-protected amine group and an octenoic acid side chain. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the precise incorporation of unique structural motifs into complex peptide sequences. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and chemical biology probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected amino acid for the automated synthesis of custom peptides.
• Pharmaceutical Research: For the development of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Design: To introduce constrained or modified backbones that mimic natural peptides for enhanced stability and bioavailability.
• Chemical Biology: As a tool compound for studying protein-protein interactions and enzyme mechanisms.
• Bioconjugation: The reactive alkene group in the side chain allows for further functionalization via click chemistry or other coupling reactions.
• Academic Research: Used in laboratories for investigating peptide structure-activity relationships (SAR).

Basic Information

Product Name	Fmoc-L-2-Methylamino-7-Octenoic Acid
CAS No.	1808268-11-2
Molecular Formula	C₂₅H₂₉NO₄
Molecular Weight	407.50 g/mol
Synonyms	Fmoc-L-2-(Methylamino)oct-7-enoic acid; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonyl](methyl)amino]oct-7-enoic acid; Fmoc-N-Me-7-Octenoic-L-acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-2-amino-7-octenoic acid; Fmoc-N-methyl-L-2-amino-7-octenoic acid; Nα-Fmoc-Nα-methyl-L-2,7-octadienoic acid; Fmoc-L-N-Me-7-Octenylglycine
EINECS	Contact for details

Quality Control

Our Fmoc-L-2-Methylamino-7-Octenoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure enantiomeric integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.