Description

2-Pyrimidinamine, 4-Chloro-n-Methyl-5-(Trifluoromethyl)- is a high-value, halogenated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique trifluoromethyl and chloro substituents impart desirable biological and physicochemical properties. It is primarily targeted at the pharmaceutical, agrochemical, and specialty chemical industries for use in medicinal chemistry and crop protection research.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Chemical Research: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and functional materials requiring specific halogenated aromatic structures.

Basic Information

Product Name	2-Pyrimidinamine, 4-Chloro-n-Methyl-5-(Trifluoromethyl)-
CAS No.	1808116-26-8
Molecular Formula	C6H5ClF3N3
Molecular Weight	211.57 g/mol
Synonyms	4-Chloro-N-methyl-5-(trifluoromethyl)pyrimidin-2-amine; 4-Chloro-2-(methylamino)-5-(trifluoromethyl)pyrimidine; 2-Amino-4-chloro-N-methyl-5-(trifluoromethyl)pyrimidine; 4-Chloro-5-(trifluoromethyl)-2-(methylamino)pyrimidine; 1808116-26-8; 4-Chloro-2-methylamino-5-trifluoromethylpyrimidine; 4-Chloro-N-methyl-5-trifluoromethyl-2-pyrimidinamine
EINECS	Contact for details

Quality Control

Our production of 2-Pyrimidinamine, 4-Chloro-n-Methyl-5-(Trifluoromethyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity determination by HPLC. A Certificate of Analysis (COA) detailing the specific results for each batch is provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.