Description

Exo-Bcn-Peg2-Boc-Amine is a specialized bifunctional linker molecule featuring an exo-BCN group and a Boc-protected amine, connected by a polyethylene glycol (PEG2) spacer. This compound is critical for advanced bioconjugation and click chemistry applications, offering controlled reactivity and enhanced solubility. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostics sectors for developing targeted drug delivery systems, antibody-drug conjugates (ADCs), and novel bioanalytical probes.

Application

• Bioconjugation & ADC Development: Serves as a key building block for constructing stable, cleavable linkers in antibody-drug conjugates and protein labeling.
• Click Chemistry Reagent: The exo-BCN group enables fast, selective, and bioorthogonal copper-free click reactions with azides for biomolecule functionalization.
• Proteomics Research: Used for site-specific modification of peptides and proteins to study structure, function, and interactions.
• Polymer & Material Science: Acts as a functional monomer or cross-linker for synthesizing smart polymers and hydrogels with tailored properties.
• Diagnostic Probe Synthesis: Employed in the fabrication of imaging agents and biosensors for in vitro and in vivo diagnostics.
• Precision Medicine Tools: Facilitates the development of targeted therapeutics and companion diagnostics.

Basic Information

Product Name	Exo-Bcn-Peg2-Boc-Amine
CAS No.	1807501-87-6
Molecular Formula	C₂₄H₄₂N₂O₆
Molecular Weight	454.61 g/mol
Synonyms	exo-BCN-PEG2-Boc-amine; (1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl (2-((2-((tert-butoxycarbonyl)amino)ethoxy)ethoxy)ethyl)carbamate; BCN-PEG2-Boc-NH₂; exo-BCN-PEG2-t-butyloxycarbonyl-amine; BCN-PEG2-Boc-amine linker; tert-Butyl (2-(2-(2-(((1R,8S,9s)-bicyclo[6.1.0]non-4-yn-9-yl)methoxy)-2-oxoethoxy)ethoxy)ethyl)carbamate
EINECS	Contact for details

Quality Control

Our Exo-Bcn-Peg2-Boc-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic nature, the container should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, Acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.