Description

2-Chloro-5-Fluoro-3-Methylbenzaldehyde is a high-purity, multi-functional aromatic aldehyde building block essential for advanced organic synthesis. Its unique halogenated and methylated structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the chloro-fluoro substitution pattern enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers where specific electronic properties are required.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Chloro-5-Fluoro-3-Methylbenzaldehyde
CAS No.	1807026-33-0
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	2-Chloro-5-fluoro-3-methylbenzaldehyde; 3-Methyl-2-chloro-5-fluorobenzaldehyde; 2-Chloro-5-fluoro-m-tolualdehyde; Benzaldehyde, 2-chloro-5-fluoro-3-methyl-; 1807026-33-0; 5-Fluoro-2-chloro-3-methylbenzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Fluoro-3-Methylbenzaldehyde is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including a detailed Certificate of Analysis (COA) with results from GC/HPLC, NMR, and IR spectroscopy to verify identity, purity, and impurity profiles. Our quality commitment ensures material traceability and consistency, supporting your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.