Description

4-Bromo-3-Fluoro-2-Iodo-Phenol is a highly functionalized halogenated phenol derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its unique combination of bromo, fluoro, and iodo substituents on the phenolic ring makes it a versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Research & Development: A valuable reagent in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution due to its differentially reactive halogen atoms.
• Ligand and Catalyst Development: Utilized for creating complex chelating ligands in coordination chemistry and catalysis.
• Fluorinated Compound Library Synthesis: Integral for constructing diverse compound libraries in high-throughput screening for drug discovery.

Basic Information

Product Name	4-Bromo-3-Fluoro-2-Iodo-Phenol
CAS No.	1807008-49-6
Molecular Formula	C6H3BrFIO
Molecular Weight	316.89 g/mol
Synonyms	2-Iodo-4-bromo-3-fluorophenol; 3-Fluoro-4-bromo-2-iodophenol; Phenol, 4-bromo-3-fluoro-2-iodo-; 4-Bromo-3-fluoro-2-iodophenol; 2-Iodo-3-fluoro-4-bromophenol
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-Fluoro-2-Iodo-Phenol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.