Description

3-Bromo-2-(Trifluoromethyl)Benzyl Alcohol is a high-value fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a reactive benzyl alcohol group with bromine and trifluoromethyl substituents, which enables precise functionalization for creating complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group is a critical pharmacophore.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) in asymmetric catalysis.
• Material Science Research: Building block for synthesizing specialty polymers, liquid crystals, or organic electronic materials with tailored properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Derivatization for Analytical Standards: Used to prepare reference standards and metabolites for analytical testing in regulatory and quality control laboratories.

Basic Information

Item	Details
Product Name	3-Bromo-2-(Trifluoromethyl)Benzyl Alcohol
CAS No.	1805950-70-2
Molecular Formula	C8H6BrF3O
Molecular Weight	255.04 g/mol
Synonyms	(3-Bromo-2-(trifluoromethyl)phenyl)methanol; 1-(Bromomethyl)-2-(trifluoromethyl)benzene-3-ol; α-(3-Bromo-2-trifluoromethylphenyl)methanol; 3-Bromo-α-(trifluoromethyl)benzenemethanol; 2-(Trifluoromethyl)-3-bromobenzyl Alcohol; 3-Bromo-2-trifluoromethylbenzyl Alcohol
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-(Trifluoromethyl)Benzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.