Description

2-Chloro-5-Methyl-4-Trifluoromethyl-Phenylamine is a high-value, halogenated aniline derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring chloro, methyl, and trifluoromethyl substituents, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a core building block for developing new herbicides, fungicides, and insecticides, leveraging the biological activity of the trifluoromethyl group.
• Material Science Research: Used in the development of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where halogen and fluorine atoms enhance lightfastness and color properties.
• Cross-Coupling Reactions: An important substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) for constructing complex biaryl amines.

Basic Information

Item	Details
Product Name	2-Chloro-5-Methyl-4-Trifluoromethyl-Phenylamine
CAS No.	1805644-84-1
Molecular Formula	C9H7ClF3N
Molecular Weight	221.61 g/mol
Synonyms	4-Amino-2-chloro-5-methylbenzotrifluoride; 2-Chloro-5-methyl-4-(trifluoromethyl)aniline; 2-Chloro-α,α,α-trifluoro-5-methyl-p-toluidine; 2-Chloro-5-methyl-4-trifluoromethylaniline; 2-Chloro-5-methyl-4-(trifluoromethyl)benzenamine; Benzenamine, 2-chloro-5-methyl-4-(trifluoromethyl)-; 4-(Trifluoromethyl)-2-chloro-5-methylaniline
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-5-Methyl-4-Trifluoromethyl-Phenylamine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.