Description

2-Bromo-3-Chloro-5-(Trifluoromethyl)Aniline is a high-purity, multi-functional halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and halogen substitution pattern makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing complex, light-fast azo dyes and high-performance pigments.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for constructing complex biaryl and heterocyclic structures.
• Contract Research & Development (CRO/CMO): Supplied to custom synthesis and process development organizations for client-specific molecule construction and scale-up projects.

Basic Information

Product Name	2-Bromo-3-Chloro-5-(Trifluoromethyl)Aniline
CAS No.	1805585-12-9
Molecular Formula	C7H4BrClF3N
Molecular Weight	274.47 g/mol
Synonyms	2-Bromo-3-chloro-5-(trifluoromethyl)benzenamine; 3-Chloro-2-bromo-5-(trifluoromethyl)aniline; Benzenamine, 2-bromo-3-chloro-5-(trifluoromethyl)-; 2-Bromo-3-chloro-alpha,alpha,α-trifluoro-p-toluidine; 5-Amino-2-bromo-1-chloro-3-(trifluoromethyl)benzene; 1-Bromo-2-chloro-4-amino-6-(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Chloro-5-(Trifluoromethyl)Aniline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, GC, NMR, and other relevant spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.