Description

2-Bromo-3-Methoxy-4-Trifluoromethoxy-Phenylamine is a high-value, multi-functional aromatic amine building block featuring bromine, methoxy, and trifluoromethoxy substituents. This unique structure makes it a critical intermediate for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its halogen and fluorine-containing groups are essential for modulating biological activity and material properties. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Acts as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its aromatic core and halogen atoms.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific properties such as flame retardancy, chemical resistance, or altered refractive index.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new chemical reactions and creating libraries of compounds for high-throughput screening.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex dyes and organic pigments, where the bromine atom facilitates further functionalization.

Basic Information

Product Name	2-Bromo-3-Methoxy-4-Trifluoromethoxy-Phenylamine
CAS No.	1805568-90-4
Molecular Formula	C8H7BrF3NO2
Molecular Weight	286.05 g/mol
Synonyms	2-Bromo-3-methoxy-4-(trifluoromethoxy)aniline; 4-Amino-2-bromo-1-methoxy-3-(trifluoromethoxy)benzene; 2-Bromo-3-methoxy-4-trifluoromethoxybenzenamine; 1-Amino-2-bromo-3-methoxy-4-trifluoromethoxybenzene; Benzenamine, 2-bromo-3-methoxy-4-(trifluoromethoxy)-; 1805568-90-4
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Methoxy-4-Trifluoromethoxy-Phenylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable supply for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.