Description

2-Bromo-3-Chloro-5-Fluorophenol is a halogenated phenol derivative, a versatile and high-value synthetic intermediate in advanced organic chemistry. Its multi-halogenated structure makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the halogen pattern contributes to biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced functional materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its ability to modify molecular polarity and conformation.
• Polymer Modification: Acts as a monomer or additive for synthesizing specialty polymers with enhanced flame retardancy, thermal stability, or specific optical properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways, catalysis, and material science applications.
• Dye & Pigment Manufacturing: Employed in the synthesis of complex halogenated dyes and pigments, offering unique color fastness and spectral characteristics.

Basic Information

Item	Detail
Product Name	2-Bromo-3-Chloro-5-Fluorophenol
CAS No.	1805518-65-3
Molecular Formula	C6H3BrClFO
Molecular Weight	225.44 g/mol
Synonyms	2-Bromo-3-chloro-5-fluorophenol; 3-Chloro-2-bromo-5-fluorophenol; 5-Fluoro-2-bromo-3-chlorophenol; Phenol, 2-bromo-3-chloro-5-fluoro-; 2-Br-3-Cl-5-F-PhOH
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Chloro-5-Fluorophenol is manufactured under strict quality management systems. We provide comprehensive quality assurance, including Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data. Our standard quality protocols ensure compliance with cGMP guidelines where applicable, and specifications can be tailored to meet specific project requirements, including pharmaceutical intermediate grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.