Description

5-Bromo-3-Fluoro-2-Iodophenol is a highly functionalized halogenated phenol derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its unique combination of bromo, fluoro, and iodo substituents on the phenolic ring makes it exceptionally valuable for introducing specific steric and electronic properties into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex heterocycles and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the halogen pattern can confer specific biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for transition metal catalysts used in cross-coupling reactions.
• Chemical Research & Development: A versatile scaffold for exploring new chemical reactions and synthesizing libraries of compounds for high-throughput screening.
• Fluorinated Compound Library: Essential for building diverse compound libraries that include fluorine atoms, a common strategy in modern drug discovery to optimize pharmacokinetic properties.

Basic Information

Product Name	5-Bromo-3-Fluoro-2-Iodophenol
CAS No.	1805500-75-7
Molecular Formula	C6H3BrFIO
Molecular Weight	316.89 g/mol
Synonyms	2-Iodo-5-bromo-3-fluorophenol; 3-Fluoro-5-bromo-2-iodophenol; Phenol, 5-bromo-3-fluoro-2-iodo-; 5-Bromo-3-fluoro-2-iodo-phenol
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Fluoro-2-Iodophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.