Description

3-Bromo-2-Chloro-5-Fluorophenol is a halogenated phenol derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for researchers and manufacturers engaged in creating active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals where precise halogen substitution patterns are required.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Chemical Research & Development: A valuable reagent for exploring new coupling reactions, such as Suzuki or Buchwald-Hartwig amination, in academic and industrial R&D labs.
• Dye and Pigment Intermediate: Employed in the synthesis of complex halogenated dyes and organic pigments.

Basic Information

Product Name	3-Bromo-2-Chloro-5-Fluorophenol
CAS No.	1805479-20-2
Molecular Formula	C6H3BrClFO
Molecular Weight	225.44 g/mol
Synonyms	2-Chloro-3-bromo-5-fluorophenol; 5-Fluoro-3-bromo-2-chlorophenol; Phenol, 3-bromo-2-chloro-5-fluoro-; 3-Bromo-2-chloro-5-fluoro-1-hydroxybenzene
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloro-5-Fluorophenol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.