Description

2-Bromo-5-Chloro-3-Fluorophenol is a halogenated phenol derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research chemists and process development scientists for the synthesis of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Employed as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Chemical Biology: Acts as a probe or labeling reagent in biochemical assays and proteomics research due to its reactive phenolic and halogen groups.
• Organic Synthesis Building Block: Facilitates cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution for introducing complex functionalities.

Basic Information

Product Name	2-Bromo-5-Chloro-3-Fluorophenol
CAS No.	1805479-11-1
Molecular Formula	C6H3BrClFO
Molecular Weight	225.44 g/mol
Synonyms	3-Fluoro-2-bromo-5-chlorophenol; 5-Chloro-2-bromo-3-fluorophenol; Phenol, 2-bromo-5-chloro-3-fluoro-; 2-Bromo-5-chloro-3-fluoro-1-hydroxybenzene; 1-Bromo-4-chloro-2-fluoro-6-hydroxybenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloro-3-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request and are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.