Description

2-Bromo-3-Fluoro-5-Methylaniline is a halogenated aniline derivative, a high-purity organic building block of significant importance in advanced chemical synthesis. Its core value lies in its unique substitution pattern, which provides a versatile and reactive scaffold for constructing complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated anilines.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for synthesizing molecular probes, enzyme inhibitors, and fluorescent tags for biological studies.
• Dye and Pigment Industry: Acts as an intermediate in the production of complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl and aryl amine structures.

Basic Information

Product Name	2-Bromo-3-Fluoro-5-Methylaniline
CAS No.	1805421-04-8
Molecular Formula	C7H7BrFN
Molecular Weight	204.04 g/mol
Synonyms	2-Bromo-3-fluoro-5-methylbenzenamine; 3-Fluoro-2-bromo-5-methylaniline; 5-Methyl-2-bromo-3-fluoroaniline; Benzenamine, 2-bromo-3-fluoro-5-methyl-; 1805421-04-8; 2-Bromo-3-fluoro-5-methyl-phenylamine; 3-Amino-4-bromo-6-fluorotoluene
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluoro-5-Methylaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.