Description

2-Bromo-4-Fluoro-3-(Trifluoromethyl)Aniline is a high-purity, multi-functional halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromo, fluoro, and trifluoromethyl substituents, makes it an indispensable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic scaffolds to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes to study biological systems.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex, halogenated dyes and pigments with specific color fastness and light-absorption properties.

Basic Information

Product Name	2-Bromo-4-Fluoro-3-(Trifluoromethyl)Aniline
CAS No.	1805249-14-2
Molecular Formula	C7H4BrF4N
Molecular Weight	258.01 g/mol
Synonyms	2-Bromo-4-fluoro-3-(trifluoromethyl)benzenamine; 1-Amino-2-bromo-4-fluoro-5-(trifluoromethyl)benzene; Benzenamine, 2-bromo-4-fluoro-3-(trifluoromethyl)-; 2-Bromo-4-fluoro-α,α,α-trifluoro-m-toluidine; 3-Amino-6-bromo-4-(trifluoromethyl)fluorobenzene; 2-Bromo-4-fluoro-3-trifluoromethylaniline
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Fluoro-3-(Trifluoromethyl)Aniline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as identity, purity (by HPLC), and levels of specific impurities. Our quality protocols are designed to support cGMP and ISO standards for reliable, batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.