Description

Pyrimidine, 2-Bromo-5-Fluoro-4-Methyl- is a high-purity, multi-functional halogenated pyrimidine building block essential for advanced organic synthesis. This compound is critical for medicinal chemistry research and development, enabling the creation of novel molecular architectures. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological mechanisms and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs serving the life sciences industry.

Basic Information

Product Name	Pyrimidine, 2-Bromo-5-Fluoro-4-Methyl-
CAS No.	1805192-57-7
Molecular Formula	C5H4BrFN2
Molecular Weight	191.00 g/mol
Synonyms	2-Bromo-5-fluoro-4-methylpyrimidine; 4-Methyl-2-bromo-5-fluoropyrimidine; 5-Fluoro-2-bromo-4-methylpyrimidine; 2-Bromo-5-fluoro-4-methyl-pyrimidine; Bromofluoromethylpyrimidine; Pyrimidine, bromofluoro methyl derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Fluoro-4-Methylpyrimidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and scale-up. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, NMR, and MS is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.